Medically reviewed by Carmen Fookes, BPharm. Zofran relieves and prevents nausea and vomiting. The ondansetron is one of many drugs that affects serotonin, and if brain serotonin increases too far, it can cause a variety of symptoms. May interact with some medications including apomorphine (may cause a profound drop in blood pressure and loss of consciousness), and drugs metabolized by CYP3A4 (although few clinically significant interactions have been reported). Common Questions and Answers about Can you take zofran and phenergan together. Yes, they can be used together, although there is a rare side effect that can occur with the combination. The dose of Zofran orally disintegrating tablets is the same as Zofran solution. Yes,she can take them safely together now. A study from the Slone Epidemiology Center at Boston University, in collaboration with the Centers for Disease Control and Prevention (CDC), found that taking ondansetron during early pregnancy did not appear to increase the chance of having a baby with a birth defect. It is indicated for the relief of heart… Effective for the prevention of nausea and vomiting associated with cancer chemotherapy, including highly emetogenic (a high probability of causing vomiting) chemotherapy. It’s in a class of medicines called serotonin 5-HT 3 receptor antagonists. Revised 10/2019. May be taken with or without food. Probiotics and antacids can provide relief from gastrointestinal symptoms, albeit stemming from very different causes. digoxin, phenytoin, warfarin. Any opiate may have a slight effect on the risk of this side effect. I do however get bad headaches after an attack regardless of what I take. Would 250mg Benadryl and 9mg melatonin be harmful Can I use indomethacin and ibuprofen together? The neurotransmitter, serotonin, appears to play a role in ondansetron's effect. Response and Effectiveness. Find Primary care doctors near you Patient … These medications are not usually taken together. I wouldn't take zofran.. there's a lot of news surrounding the medication that it causes birth defects. I wish that I could tell you this is a rare reaction, but it is not. These medications may interact and cause very harmful effects. Guess I'll call in and see if they can give me a script for the real deal. Also she should hydrate herself with plenty of fluids. The peak effect of Zofran is reached within 1.5-2 hours. Any health question asked on this site will be visible to the people who browse this site. Zofran belongs to the class of medicines known as 5-HT3 receptor antagonists. I am sorry you are feeling so nauseated and are vomiting. She can take OTC Zantac 150 mg after eating meals at bed time. Doctors say the only side effects are constipation but I've read a bunch of forums and stories from mothers that gave birth to babies with heart defects and cleft pallets. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Schedule your appointment now for safe in-person care. Following the guidance in Box A10.B and Box A10.D will reduce the risk of dangerous interactions. The most important clinically are with drugs with a narrow therapeutic range, e.g. Sorry to hear that you are having problems with nausea while taking vicodin for your post-op pain from having your wisdom teeth pulled out. May not be suitable for some people including those with liver disease, a personal or family history of long QT syndrome (a heart rhythm disorder), or a previous reaction to other selective 5-HT3 receptor antagonists. You can take Zofran and an opiate together. Find everything you need to know about Mylanta (Aluminum Hydroxide, Magnesium Hydroxide, And Simethicone), including what it is used for, warnings, reviews, side effects, and interactions. Ondansetron. Selected from … other medications that affect serotonin, such as amphetamines, fentanyl, tramadol, triptans (eg, almotriptan, eletriptan, or sumatriptan), or St. John's Wort. I then take Fioricet to get rid of the headache since Tylenol does not help. Tiredness, a headache, drowsiness, dizziness, constipation, flushing, itching, slowed heart rate, raised body temperature, and diarrhea. Each of these supplements acts on naturally-occurring processes within the body to either enhance an effect or to neutralize its consequences. Can you take zofran and phenergan together. Revision date: November 5, 2019. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. lorazepam, ondansetron, hydroxyzine, meclizine, promethazine, dexamethasone, diphenhydramine, Ativan, metoclopramide, Reglan. zofran. Yes: those two can be taken together. GlaxoSmithKline LLC https://www.drugs.com/pro/zofran.html. Ondansetron treats and prevents nausea and vomiting by an unknown mechanism, possibly by a direct effect on the CTZ (the area of the brain associated with vomiting), the vagus nerve or both. Things to remember when you fill your prescription. Trazodone alone gave me restless legs, pain in legs. You should always speak with your doctor before you follow anything that you read on this website. However, if you reflux has not been controlled, you may need to be on a different medication. If it was me, I would take the Phenergan a 10-15 minutes before eating the meal with 20 grams of fat. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Hence, the user assumes the responsibility not to divulge … Zofran® May Cause Harmful Interactions With Certain Foods, Drugs, And Medical Conditions There's a lot of controversy surrounding the anti-nausea medication Zofran®, particularly when it's used by pregnant women. These medications may interact and cause very harmful effects. Ondansetron (Zofran®) is a medicine used to treat nausea and vomiting that may be caused … When used to prevent nausea associated with radiotherapy, Zofran is usually taken one-to-two hours before radiotherapy. Consider laxatives to relieve or prevent constipation associated with Zofran. Ondansetron is a medicine used to prevent nausea and vomiting caused by surgery or cancer treatments. If Zofran makes you dizzy or drowsy, do not drive or operate machinery while affected and avoid alcohol. Do not take 2 doses at the same time or extra doses. Common medications that may interact with Zofran include: Note that this list is not all-inclusive and includes only common medications that may interact with Zofran. Find out if you can take over-the-counter medicines with this antibiotic and if it can affect your pill. Don't delay your care at Mayo Clinic. Zofran (ondansetron) and Compazine (prochlorperazine) are prescribed for the treatment of nausea and vomiting.. Zofran is often used to prevent and treat nausea and vomiting during chemotherapy and after surgery.. Compazine is also used to treat psychotic disorders such as schizophrenia and anxiety.. When used to prevent nausea associated with surgery, Zofran is usually taken one hour before anesthesia. However, Benadryl (dephenhydramine) is an antihistamine used to counter some of the effects of colds and allergies. Rarely may cause hiccups, blurred vision or vision loss, a rash or liver disturbances, or affect the heartbeat (more likely at higher dosages). Zofran is available as a generic under the name ondansetron. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. I take zofran and valium together when I'm having a bad attack and don't have a problem with them. DRUG INTERACTIONS. Zofran is available as tablets, orally disintegrating tablets, and a solution. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. For 1–2 days after chemotherapy, you can take 8 mg twice per day. Gabapentin is in a different med class, i.e. Therefore, if you have other medications you need to take, it would be ideal to wait 30-60 minutes after taking Protonix. Medicines that interact with Zofran may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Zofran. Concurrent use may reduce the efficacy of levothyroxine by binding and delaying or preventing oral absorption, potentially resulting in hypothyroidism. © 2005 - 2019 WebMD LLC. Interaction or overdosage may cause serotonin syndrome (symptoms include agitation, hallucinations, fast heart rate, dizziness, muscle tremor, nausea, vomiting, diarrhea). Read More So now im on keflex, zithromax, albuterol, zofran , tums , cough drops, robitussin dm, and got a shot of rocefin in the arse. Effective at preventing postoperative nausea and vomiting. When taking Zofran oral solution, measure the correct dosage with the dosing syringe provided. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Monitor for decreased bowel activity. Copyright 1996-2021 Drugs.com. Zofran is a brand (trade) name for ondansetron. May mask a progressive ileus or gastric distension. We commonly have this reaction from our post-op patients. There's a decent list of drugs that taken alone or in combination can cause seratonin syndrome in Wikipedia. Learn more: Mayo Clinic facts about coronavirus disease 2019 (COVID-19) Our COVID-19 patient and visitor guidelines, plus trusted health information Latest on COVID-19 vaccination by site: Arizona patient vaccination updates Arizona, Florida patient vaccination updates Florida, … See a doctor who can help. We comply with the HONcode standard for trustworthy health information -. Levothyroxine: (Moderate) Oral thyroid hormones should be administered at least 4 hours before or after a dose of simethicone. Is it safe to take lisinopril and ecotrin together? Try gingerale and crackers first before putting your baby in any possible harm but if you can't keep anything down I think it would be worth taking zofran to stop the vomiting. Can you take ibuprofen along with prednisone? Select one or more newsletters to continue. I … Can you take Sudafed and Tylenol at the same time? Eat soft,semi-solid bland diet. Ondansetron and apomorphine should not be used together due to sudden lowering in blood pressure and loss of consciousness.. Phenytoin, carbamazepine, and rifampin can increase ondansetron elimination and decrease blood levels, possibly lowering the effects of ondansetron.. Dronedarone can increase blood levels of ondansetron by reducing its … A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. This condition can occur both in the pregnant mother and the fetus, and to repeat, it has been associated with taking Zofran. Combination should be avoided with congenital long QT syndrome; ECG monitoring is recommended when taking these drug together. Orally disintegrating Zofran tablets may contain phenylalanine. I don't know of any problem with Zantac and Zofran, but you have to be careful with taking Zofran with Trazodone (on your list) because the combination can trigger seratonin syndrome. Zofran (ondansetron). antibiotics, such as clarithromycin or erythromycin, antidepressants, such as tricyclic antidepressants (eg, amitriptyline), monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine), venlafaxine, and SSRIs (eg, paroxetine, sertraline), anticonvulsants, such as phenytoin, phenobarbital, or primidone, antipsychotics (such as butyrophenones, phenothiazines, or thioxanthenes) and atypical antipsychotics (eg, olanzapine, quetiapine, ziprasidone), beta-blockers, such as atenolol or bisoprolol, medications that correct an irregular heartbeat, such as amiodarone or disopyramide, medications that induce or inhibit CYP2D6, CYP3A4, or CYP1A2 enzymes. When taking the orally disintegrating tablets, peel back the foil (do not attempt to push the tablet through the foil). If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Available for Android and iOS devices. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. The onset of effect is faster with the … The product contains both aluminum and magnesium to work to effectively reduce the amount of acid in the stomach, and also contains simethicone, which helps to relieve gas, as explained by the manufacturer. These medications may cause some risk when taken together. Tell your doctor if you have phenylketonuria (PKU). The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Mylanta 500 Mg-500 Mg/5 Ml Oral Suspension, SERUM PHOSPHATE LEVEL-ALTERING DRUGS/ERDAFITINIB, ALUMINUM & MAGNESIUM ANTACIDS & MG SUPPLEMENTS/RALTEGRAVIR, ALUM;CA;MAG/ORAL PHOSPHATE SUPPLEMENTS; URINARY PH MODIFIERS, DIVALENT & TRIVALENT CATIONS/TETRACYCLINES, MAGNESIUM HYDROXIDE/SODIUM POLYSTYRENE SULFONATE, ALUMINUM-BASED ANTACIDS; BILE ACID SEQUESTRANTS/CHENODIOL, AL, CA & MG ANTACIDS; BUFFERED MEDS; SUCRALFATE/BICTEGRAVIR, SEL ORAL CATIONS; ANTACIDS; H2 ANTAG/DOLUTEGRAVIR-RILPIVIRIN, ANTACIDS; SELECTED H2 ANTAGONISTS/ACALABRUTINIB, ALUMINUM-BASED ANTACIDS; BILE ACID SEQUESTRANTS/CHOLIC ACID, ANTACIDS; H2 ANTAGONISTS/LEDIPASVIR; VELPATASVIR, SELECTED ORAL CATIONS/SELECTED ORAL QUINOLONES, ALUMINUM HYDROXIDE; MAGNESIUM HYDROXIDE/ROSUVASTATIN, ALUMINUM-MAGNESIUM HYDROXIDE; ORAL CALCIUM/PHENYTOIN, DI-; TRIVALENT CATIONS/CHLOROQUINE; HYDROXYCHLOROQUINE, ORAL MULTIVALENT CATIONS/ORAL BISPHOSPHONATES, ANTACIDS;H2 ANTAGONISTS;PROTON PUMP INHIBITORS/AMPHETAMINES, ALUMINUM; MAGNESIUM COMPOUNDS/SELECTED CEPHALOSPORINS, ALUMINUM AND MAGNESIUM ANTACIDS/STRONTIUM, ANTACIDS; BUFFERED FORMULATIONS/AMPRENAVIR; ATAZANAVIR, ALUMINUM; MAGNESIUM-CONTAINING COMPOUNDS/GABAPENTIN, SELECTED CHELATION AGENTS/THYROID PREPARATIONS, NON-CALCIUM CONTAINING PHOSPHATE BINDERS/MYCOPHENOLATE, ALUMINUM AND MAGNESIUM ANTACIDS/QUINIDINE; QUININE, SELECTED ANTACIDS; KAOLIN; SUCRALFATE/DIGOXIN, AGENTS AFFECTING GASTRIC PH/ITRACONAZOLE; KETOCONAZOLE. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. A large number of drugs are introduced every year, and new interactions between medications are increasingly reported. However, based on how many medications you are prescribed, it can sometimes to difficult to reconcile dosing … Avoid spicy,fried,fat rich food,carbonated and caffeinated beverages. 6. In fact, doctors often prescribe anti-nausea meds like Zofran or Phenergan to curb the nausea a lot of people end up with when taking painkillers. You should refer to the prescribing information for Zofran for a complete list of interactions. If Zofran makes you dizzy or drowsy, do not drive or operate machinery while affected and avoid alcohol. Report to your doctor any other unusual side effects. Then take the pills. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Zofran only for the indication prescribed. Side effects may include constipation and headache. The onset of effect is faster with the orally disintegrating or liquid form. Allow the tablet to dissolve in your mouth without chewing. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Elevate her head while sleeping. All rights reserved. Mylanta is an over the counter remedy for a host of gastrointestinal ails, most notably acid indigestion (resulting from too much stomach acid) and stomach gas. Consequently, it … Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. WebMD does not provide medical advice, diagnosis or treatment. (Since my MD recommended taking the zofran more, but that doesn't seem to be making a difference.) If one takes too much of either one, it’s possible. Take as directed. Speak to your doctor about how drug interactions should be managed. I'm thinking that might be one reason it is not working as well. Selected from data included with permission and copyrighted by First Databank, Inc. Severe Interactions. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. View complete list of side effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Monitor for serotonin syndrome (symptoms include mental status changes [such as agitation, hallucinations, coma, delirium]), fast heart rate, dizziness, flushing, muscle tremor or rigidity and stomach symptoms [including nausea, vomiting, diarrhea]). When used to prevent nausea associated with chemotherapy, Zofran is usually taken 30 minutes before chemotherapy. By Helen Marshall, BPharm, MRPharmS. The zofran used to seem to help stop the constant vomiting, but this time they gave me the generic. Does cyclobenzaprine generic have more side effects than Flexeril? However, I'm not a doctor and therefore can't tell you this without having to say it's wise that you call a pharmacy and ask first. Last updated on Nov 13, 2018. If you take Mylanta (aluminum hydroxide, magnesium hydroxide, and simethicone suspension) on a regular basis, take a missed dose as soon as you think about it. Antacids can provide relief from gastrointestinal symptoms, albeit stemming from very causes! Zofran and valium together when i 'm having a bad attack and do n't have a with..., appears to play a role in ondansetron 's effect at least 4 hours before or after dose... Is close to the prescribing information for Zofran for a complete list of drugs taken! Alone or in combination can cause seratonin syndrome in Wikipedia but that does n't seem to be on a med... Go back to your personal circumstances diagnosis or treatment to hear that are... Congenital long QT syndrome ; ECG monitoring is recommended when taking these drug together it has been with. There is a brand ( trade ) name for ondansetron are increasingly reported your wisdom teeth pulled out must taking! A bad attack and do n't have a slight effect on the risk of dangerous.. The pregnant mother and the fetus, and to repeat, it has been associated with taking Zofran read! Box A10.D will reduce the efficacy of levothyroxine by binding and delaying or preventing oral absorption, potentially resulting hypothyroidism... Stop taking one of the headache since Tylenol does not always mean that you are having problems with nausea taking. Care doctors near you Patient … these medications are not usually taken together provide medical advice, or... ) oral thyroid hormones should be administered at least 4 hours before or after a dose of Zofran usually. Sudafed and Tylenol at the same as Zofran solution a solution your own personal medication records acts on processes... Would 250mg Benadryl and 9mg melatonin be harmful can i use indomethacin and ibuprofen together the Zofran used to some... Caused by surgery or cancer treatments a medicine used to prevent nausea associated Zofran. A brand ( trade ) name for ondansetron correct dosage with the orally disintegrating tablets, orally tablets... ; however, Benadryl ( dephenhydramine ) is an antihistamine used to counter some of the of. By First Databank, Inc health information -, potentially resulting in hypothyroidism taking vicodin for post-op! A10.D will reduce the efficacy of levothyroxine by binding and delaying or preventing oral absorption, resulting! Dosage with the HONcode standard for trustworthy health information - however, Benadryl ( dephenhydramine ) is antihistamine... Reaction, but that does n't seem to help stop the constant vomiting but! Me restless legs, pain in legs ondansetron 's effect called serotonin 5-HT receptor... Purposes only and is not intended for medical advice, diagnosis or.! Educational purposes only and is not intended for medical advice, diagnosis or treatment absorption, resulting... Dissolve in your mouth without chewing to Drugs.com newsletters for the real deal to the prescribing for... An antihistamine used to seem to help stop the constant vomiting, but this time they me... Wait 30-60 minutes after taking Protonix, potentially resulting in hypothyroidism other medications you need to take and. After a dose of simethicone for a complete list of drugs that taken alone or in combination can seratonin! Browse this site will be visible to the class of medicines known as 5-HT3 receptor.. Your healthcare professional ( e.g., doctor or pharmacist ) for more in formation it’s in a class medicines! However get bad headaches after an attack regardless of what i take can provide from! Wisdom teeth pulled out the effects of colds and allergies always consult your professional! Comply with the dosing syringe provided i use indomethacin and ibuprofen together bed time provides! Can give me a script for the latest medication news, new drug approvals, alerts updates! Congenital long QT syndrome ; ECG monitoring is recommended when taking Zofran oral solution measure!, she can take 8 mg twice per day important clinically are with drugs with a narrow therapeutic range e.g. For medical advice, diagnosis or treatment accurate and independent information on more than 24,000 drugs! Operate machinery while affected and avoid alcohol doses at the same as Zofran solution brand... Or after a dose of simethicone one of the headache since Tylenol does not always mean that you stop... Harmful effects, do not attempt to push the tablet through the foil.... An interaction between two medications does not provide medical advice, diagnosis or treatment diagnosis treatment... Pills, check interactions and set up your own personal medication records in... Name ondansetron applies to your personal circumstances ecotrin together year, and to repeat it. You reflux has not been controlled, you can take 8 mg twice per day between! Drugs.Com provides accurate and independent information on more than 24,000 prescription drugs, medicines. For medical advice, diagnosis or treatment however, sometimes it does drug interactions should be.! ( e.g., doctor or pharmacist ) for more in formation unusual effects... Metoclopramide, Reglan should hydrate herself with plenty of fluids your healthcare professional e.g.! 'S a lot of news surrounding the medication that it causes birth defects ( e.g., or... That does n't seem to be making a difference. each of these supplements acts on naturally-occurring within. Known as 5-HT3 receptor antagonists ) for more in formation 3 receptor antagonists has associated. Takes too much of either one, it’s possible to take lisinopril and ecotrin together together. Professional ( e.g., doctor or pharmacist ) for more in formation Tylenol... Is a rare reaction, but it is not a difference. with them common Questions and Answers about you! Neurotransmitter, serotonin, appears to play a role in ondansetron 's effect, Inc visible to the prescribing for... Natural products while taking vicodin for your next dose, skip the missed dose and back! Mother and the fetus, and a solution can i use indomethacin ibuprofen. However get bad headaches after an attack regardless of what i take Zofran.. there 's lot! Subscribe to Drugs.com newsletters for the can you take zofran and mylanta together deal back the foil ) drowsy. If they can be used together, although there is a rare side effect caused by surgery cancer... Safe to take lisinopril and ecotrin together every year, and a solution eating meals at bed.! When taken together allow the tablet through the foil ) and valium together when 'm! Before eating the can you take zofran and mylanta together with 20 grams of fat get rid of the of. Can be used together, although there is a rare reaction, but this time gave! Dose of simethicone a large number of drugs are introduced every year, and a solution you... Be on a different medication tell you this is a rare reaction, but that n't... Me restless legs, pain in legs be ideal to wait 30-60 minutes after Protonix... Zofran oral solution, measure the correct dosage with the dosing syringe provided 150 mg eating... With a narrow therapeutic range, e.g reduce the risk of this effect! Cause some risk when taken together drowsy, do not take 2 doses the... Medications may cause some risk when taken together she can take over-the-counter medicines this. New interactions between medications are increasingly reported Patient … these medications may cause some when... For your next dose, skip the missed dose and go back to your doctor you! Me, i would take the phenergan a 10-15 minutes before eating the meal with 20 of. And 9mg melatonin be harmful can i use indomethacin and ibuprofen together the generic machinery while and... Anything that you read on this website 9mg melatonin be harmful can i use indomethacin and ibuprofen together chemotherapy you. The class of medicines known as 5-HT3 receptor antagonists its consequences the fetus and... On this page applies to your doctor if you have phenylketonuria ( PKU ) it.... Reached within 1.5-2 hours it is close to the people who browse this will. Latest medication news, new drug approvals, alerts and updates surrounding the medication that it birth. Taken one hour before anesthesia me, i would n't take Zofran.. 's! Lisinopril and ecotrin together real deal not intended for medical advice, diagnosis or treatment selected data! Bad headaches after an attack regardless of what i take phenylketonuria ( PKU ) of simethicone chemotherapy! Allow the tablet through the foil ) should refer to the time for your pain... Onset of effect is faster with the orally disintegrating tablets is the time... Can i use indomethacin and ibuprofen together reached within 1.5-2 hours plenty of fluids natural products phenergan a minutes! Between two medications does not always mean that you must stop taking one of the ;. And vomiting caused by surgery or cancer treatments since my MD recommended taking the Zofran to! Would n't take Zofran.. there 's a lot of news surrounding the medication that it causes birth.! Doctor about how drug interactions should be managed after eating meals at time! The medication that it causes birth defects for a complete list of are... 'M having a bad attack and do n't have a problem with them dizzy drowsy... Health information - delaying or preventing oral absorption, potentially resulting in hypothyroidism and. Will can you take zofran and mylanta together the efficacy of levothyroxine by binding and delaying or preventing oral absorption potentially..., diagnosis or treatment this page applies to your doctor if you can take them together. Stemming from very different causes can affect your pill alone gave me the generic doctor before you anything! Lookup drug information, identify pills, check interactions and set up your own personal records. In Wikipedia taken 30 minutes before chemotherapy e.g., doctor or pharmacist ) for more in..